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Non-human primate models for understanding the impact of the microbiome on pregnancy and the female reproductive tractAbstract The microbiome has been shown, or implicated to be involved, in multiple facets of human health and disease, including not only gastrointestinal health but also metabolism, immunity, and neurology. Although the predominant focus of microbiome research has been on the gut, other microbial communities such as the vaginal or cervical microbiome are likely involved in physiological homeostasis. Emerging studies also aim to understand the role of different microbial niches, such as the endometrial or placental microbial communities, on the physiology and pathophysiology of reproduction, including their impact on reproductive success and the etiology of adverse pregnancy outcomes (APOs). The study of the microbiome during pregnancy, specifically how changes in maternal microbial communities can lead to dysfunction and disease, can advance the understanding of reproductive health and the etiology of APOs. In this review, we will discuss the current state of non-human primate (NHP) reproductive microbiome research, highlight the progress with NHP models of reproduction, and the diagnostic potential of microbial alterations in a clinical setting to promote pregnancy health. NHP reproductive biology studies have the potential to expand the knowledge and understanding of female reproductive tract microbial communities and host–microbe or microbe–microbe interactions associated with reproductive health through sequencing and analysis. Furthermore, in this review, we aim to demonstrate that macaques are uniquely suited as high-fidelity models of human female reproductive pathology. Biology of Reproduction, ioad042, https://doi.org/10.1093/biolre/ioad042 Published: 11 April 2023 I am honored to have received a travel award and be selected to give a short talk at the joint symposia on Infections in Pregnancy and Maternal-Fetal Crosstalk.
I am excited to be joining the board of directors as the Vice President of the Endosalpingiosis Foundation Inc non-profit. I will be running their social media and web accounts, as well as content creation and design for advocacy, outreach, and fundraising. To learn more, check out our website EnsosalFoundation.org or follow on Instagram @endosalgal and @endosal_foundation During Covid I dedicated myself to a few online communities and content creation for causes I hold dear. I am Honored that I was selected as an Honorary Mention in the 2022 Digital Media Contest and be featured for a week at UW Libraries & online here.
Acute Exposure to the Food-Borne Pathogen Listeria monocytogenes Does Not Induce α-Synuclein Pathology in the Colonic ENS of Nonhuman PrimatesAuthors Mancinelli AM, Vichich JM, Zinnen AD, Hugon AM, Bondarenko V, Metzger JM, Simmons HA, Golos TG, Emborg ME
Journal Journal of Inflammation Research Accepted for publication 1 December 2021 Published 22 December 2021 Volume 2021:14 Pages 7265—7279 DOI https://doi.org/10.2147/JIR.S33754 New Abstract & Research Title: Maternal gut microbiome divergence in cynomolgus macaques during early pregnancy with listeriosis Manuscripts in Progress: Nonhuman Primates as ideal model for reproductive microbiome research: A unique insight into microbial presence during pregnancy Honolulu, Hawaii and Anaheim California here I come! I am so excited to travel to BOTH huge conferences this year. I can't wait to meet with other STEMinists and activists in science! I follow quite a few people on twitter who will also be in attendance. I am fortunate to represent CMP & SciMed GRS at our UW-Madison exhibit booth during both conferences. Come by to chat about opportunities in Madison. Check out my social media @AnnaMarie4PhD
Do you ever just wish you had your own personal logo? Well I did. When I was younger, I began to initial all of my art or creative endeavors with a single swipe initials AMR. Since then, it has become my identifier, on lab notebooks, labels, or documents. Following the new trends in STE(Art)M, I decided to integrate my art and my science... To celebrate completing my second year of graduate school and no more classes, I decided to get creative and am excited to unveil my new personal logo! This will be on my marketing tools, including business cards and online materials starting in the Fall!! The design is based upon "agar art" which is a new term microbiologist are using on social media in #scicomm to describe bacterial agar growth plates with the bacteria is drawn on in a design. I highly suggest you google it! Below are some fun examples of agar art (I do not own or claim any of the photos below as my own). |
Purpose:Occasional updates on my current presentations and projects. Archives
September 2023
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